EXPOSURE TO HYCANTHONE ALTERS CHROMATIN STRUCTURE AROUND SPECIFIC GENE FUNCTIONS AND SPECIFIC REPEATS IN SCHISTOSOMA MANSONI

Exposure to Hycanthone alters chromatin structure around specific gene functions and specific repeats in Schistosoma mansoni

Schistosoma mansoni is a parasitic plathyhelminth responsible for intestinal schistosomiasis (or bilharziasis), a disease affecting 67 million people worldwide and causing an important economic burden.The schistosomicides hycanthone, and its later proxy oxamniquine, were widely used for treatments in endemic areas during the 20th century.Recently,

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HCV microelimination in harm reduction centres has benefits beyond HCV cure but is hampered by high reinfection rates

Background & Aims: Significant scale-up of treatment among people who inject drugs (PWID) is crucial to achieve WHO HCV elimination targets.We explored the impact of on-site HCV diagnosis and treatment on PWID in an externalised hepatology clinic at the biggest harm reduction centre (HRC) in Barcelona attending to a marginalised PWID Cloth Harn

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